Microbiota bacterial strains are like skilled workers on an assembly line. Only if they are in the right place, are they able to do their job professionally, become skilled in "team working" and make the assembly line fluid and well-functioning. This condition is known as eubiosis.
In an healthy microbiota the bacteria within it produce an adequate quantity of short-chain fatty acids (SCFA), which are generated by the fermentation of dietary fiber (No dietary fiber = few SCFAs). The primary SCFAs produced by the microbiota are acetic, propionic and butyric. Microbiota-produced SCFAs are primarily acetic, propionic and butyric acids.
These small molecules communicate directly with the epithelial cells of the colon and regulating nutrient metabolism and host homeostasis. They also play an important role in the regulation of cell proliferation and in phagocytosis. SCFAs also help control the production of free radicals and reactive oxygen species (ROS), facilitate the synthesis and maintenance of the cells’ tight junctions (TJ), which are essential in keeping the epithelial cells well-attached and reducing the passage of bacterial fragments into the bloodstream (something that occurs when the state of eubiosis is no longer optimal).
Stress, infections, drug and antibiotic abuse, food-preservatives, pesticides, food-dyes and obviously, a disorderly and nutrient-poor diet, can all have an adverse effect on the condition of the intestine by causing a depletion of microbial diversity and an increase in unwanted bacterial species that can negatively impact human health over time.
Keeping the gut microbiota in a state of eubiosis with a "microbiota-friendly" diet will contribute to making one’s life healthier and less stressful.